This study empirically tested the influence of liquidity, operational costs, to profitabilitas in mining sector companies listed in Indonesia Stock Exchange 2011-2015. The problem with mining companies is the decline in Problems that occur in mining companies is the decline in profitability despite liquidity decreased, operating costs decreased.The research method that is used is descriptive analysis method verifikatif with unit of analysis researched is financial report of mining sector companies listed in BEI in year 2010-2015. And the population of 23 Purposive Sampling and obtained sample research as many as 30 financial reports from 6 companies. This research that liquidity has a significant affecting on profitability with a negative relationship, operational costs have a significant effect on profitability with a positive relationship with a positive relationship.Partially profitability dominant influenced by operational cost compared with liquidity.